Solubility and Permeability Studies of Aceclofenac in Different Oils

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Solubility and Permeability Studies of Aceclofenac in Different Oils

Purpose: To measure the extent of solubility of the lipophilic drug, aceclofenac, in 13 oils as well as its in vitro permeability from these oils in order to develop optimized topical microemulsion and microemulsion-based gel for improved bioavailability. Methods: UV spectrophotometeric method was used at the wavelength of 276 nm to measure the dissolved quantity of aceclofenac in each of the o...

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2014

ISSN: 1596-9827,1596-5996

DOI: 10.4314/tjpr.v13i3.2